Endocytosis of Charged Electrically Nano Drugs Described by Boltzmann Equation

Abstract

Once a volume of nanoparticles have been released by cargo close to tumor cells, it is desired to expect that a big fraction of them reaches its internalization through a successful endocytosis. Because central purpose of Oncological nanomedicine targets destruction of tumor, it is deeply desired that engineered nanoparticles turn off secondary electrical inter-actions in order to optimize their objective. In this paper, the phase seen as to be previous to uptake of cell, carried by an electrically charged nanoparticle is modeled by the Boltzmann equation. While the pure kinetic part would correspond to space far from target cell, the dynamical part would be of interest since it would model the acceptation or rejection of drugs to be successfully internalized.