Inherent Biolectrical Circuits in Neural Synapse

Abstract

This paper proposes the idea that neural synapse is a pure electrical event. In order to derive this the well-known Fokker-Planck equation is employed. Basically the process of synapse is divided in three phases: (i) The transit of synaptic vesicles to the axon zone, (ii) the releasing of neurotransmitters in the cleft zone, and (iii) the transfer of neurotransmitters to the adjacent neuron through the ion channels. The dynamics equation is expressed as function of the volumetric charge density. Once the electrical variables have been defined the respective permittivities are associated to each zone where exists transit of neurotransmitters. The time derivative of resulting electric charge is interpreted as the current that is created by the pass of neurotransmitters from a neuron to another in full concordance to the current concepts of synapse. Indeed, under the present treatment is is possible to identify the cases where exists accumulation of neurotransmitters along the cleft zone, fact that would suggest the idea that the obstruction of neurotransmitters breaks down synapse. Therefore, such blocking might be well related to neurological diseases. Analysis of the created currents are presented.